CytogenLympho is a specialized medium for cytogenetic diagnosis using lymphocyte cultures. Supplied as a frozen, homogeneous, “ready-to-use” medium, it eliminates pipetting errors and minimizes the risk of contamination.

This precisely formulated medium is based on an optimized basal medium and contains all the essential components for maximum cell growth: antibiotics (penicillin/streptomycin) & L-glutamine, pre-tested fetal bovine serum (FBS), optimized phytohemagglutinin (PHA) as a mitogen, and phenol red (pH indicator)

Your diagnostic advantage:
CytogenLympho specifically promotes mitosis induction and accelerates the proliferation of lymphocytes from heparinized blood and lymphocyte-enriched blood.
The result: You obtain usable metaphases more quickly, enabling earlier and more reliable chromosome analysis.

Features and Benefits at a Glance

100% ready to use: No need to prepare individual components (requires in-house validation), no sources of error—ready for use immediately after thawing.
Optimized growth: Significantly improved yield thanks to a specifically tailored PHA fraction and concentration.
Faster diagnosis: Shortened cultivation time with reliable cell harvest for efficient workflows.
Clear results: High mitotic index rates for precise cytogenetic findings.
Versatile application: Suitable for heparinized whole blood and lymphocyte-enriched blood.

Regulatory Compliance & Quality Assurance
CytogenLympho strictly complies with the requirements of Directive 98/79/EC and bears the CE mark as an in vitro diagnostic (IVD).

Note on Validation: In accordance with Good Laboratory Practice (GLP), it is recommended that each new medium be validated under specific local laboratory conditions before being introduced into routine diagnostic use to ensure optimal performance within your own workflow.

Technical Specifications & Quality Controls
Each batch is rigorously tested to ensure the highest level of safety:

pH-Wert: Stabil eingestellt zwischen 7,0 und 7,5
Osmolalität: 280 bis 340 mOsmol/kg
Endotoxin-Gehalt: < 25 EU/ml
Mykoplasmen: Negativ
Sterilität: Geprüft und frei von Keimen/Bakterien/Pilzen
Haltbarkeit: 15 Monate ab Herstellungsdatum (bei korrekter Lagerung)
Zusatzanwendung: CytogenLympho eignet sich zudem für die genotoxische Prüfung gemäß OECD-Richtlinien (OECD 487 & OECD 473, Stand 29.07.2016).

Transport and Storage
To ensure the components remain fully effective, the medium must be stored and transported at a temperature of ≤ -18°C at all times.